| (CCTG) IND.241 - Master Protocol | A Liquid-biopsy Informed Platform Trial to Evaluate Treatment in CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer | Dr Nidhi Kumar-Tyagi | Suspended/On hold | NCT05601440 (Master) |
| (CCTG) IND.241A / Sub-Study A | Liquid-Biopsy Monitoring for Patients not yet Eligible for Screening and Enrollment | Dr Nidhi Kumar-Tyagi | Suspended/On hold | NCT05601440 (A) |
| (CCTG) IND.241B / Sub-Study B | A Phase II Study of RP-6306 in Patients with CDK4/6-Inhibitor Treated ER+HER2- Metastatic Breast Cancer Receiving Gemcitabine | Dr Nidhi Kumar-Tyagi | Suspended/On hold | NCT05601440 (B) |
| (CCTG) IND.241C / Sub-Study C | A Phase II Study of Niraparib, A PARP Inhibitor, in Patients with CDK4/6-Inhibitor Treated ER+/HER2- Metastatic Breast Cancer | Dr Nidhi Kumar-Tyagi | Suspended/On hold | NCT05601440 (C) |
| (CCTG) MA.39 / TAILOR RT | A randomized trial of regional radiotherapy in Biomarker low risk node positive breast cancer (TAILOR RT) | Dr Timothy Whelan | Open to recruitment | NCT03488693 |
| (Roche) WO43919 / INAVO121 | A Phase III, Multicenter, Randomized, Open-Label Study Evaluating The Efficacy And Safety Of Inavolisib plus Fulvestrant versus Alpelisib plus Fulvestrant In Patients With Hormone Receptor positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Who Progressed During Or After CDK4/6 Inhibitor and Endocrine Combination Therapy | Dr Haider Samawi | Open to recruitment | NCT05646862 |
| OCOG-2019-RHEAL | Randomized Trial of Hypofractionated LocoRegional Radiotherapy in Breast Cancer and Lymphedema (RHEAL) | Dr Timothy Whelan | Open to recruitment | NCT04228991 |
| OCOG-2021-ELISA | Prospective Evaluation of Breast-Conserving Surgery Alone in Low-Risk Ductal Carcinoma in Situ Defined by a Molecular Expression Assay Combined with Clinico-Pathological Features (ELISA Study) | Dr Timothy Whelan | Open to recruitment | NCT04797299 |
| OCOG-2022-RAPID2 | A Randomized Trial of Five-Fraction Partial Breast Irradiation (RAPID2) | Dr Do-hoon Kim | Open to recruitment | NCT05417516 |
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