Gastrointestinal

Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(CCTG) CO.29 / DYNAMIC IIICirculating Tumor DNA Analysis Informing Adjuvant Chemotherapy in Stage III Colon Cancer: A Multicentre Phase II/III Randomised Controlled Study (DYNAMIC III)Goffin, Dr JohnOpen to recruitmentACTRN12617001566325
(CCTG) CRC.9 / NRG-GI005Phase II/III Study of Circulating tumOr DNA as a Predictive BiomarRker in Adjuvant Chemotherapy in Patients with Stage IIA Colon Cancer (COBRA)Meyers, Dr BrandonOpen to recruitmentNCT04068103
(CCTG) PAC.3 / ALLIANCE A021806A Phase III Trial of Perioperative versus Adjuvant Chemotherapy for Resectable Pancreatic CancerSerrano, Dr PabloOpen to recruitmentNCT04340141
(Merck) MK-7902-015 / LEAP 015A Phase 3, Randomized Study to Evaluate the Efficacy and Safety of Lenvatinib (E7080/MK-7902) plus Pembrolizumab (MK-3475) plus Chemotherapy Compared with Standard of Care Therapy as First-line Intervention in Participants with Advanced/Metastatic Gastroesophageal Adenocarcinoma. Juergens, Dr RosalynOpen to recruitmentNCT04662710
(Roche) MO42541 / IMbrave251A PHASE III, OPEN-LABEL, RANDOMIZED STUDY OF ATEZOLIZUMAB WITH LENVATINIB OR SORAFENIB VERSUS SORAFENIB OR LENVATINIB ALONE IN HEPATOCELLULAR CARCINOMA PREVIOUSLY TREATEDWITH ATEZOLIZUMAB AND BEVACIZUMABMeyers, Dr BrandonOpen to recruitmentNCT04770896
(CCTG) CO.21 / CHALLENGEA Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE)Goffin, Dr JohnSuspended/On holdNCT00819208
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