Gastrointestinal

Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(H3 Biomedicine and Eisai) H3B-6527-G000-101An Open-Label Multicenter Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Subjects With Advanced Hepatocellular CarcinomaMeyers, Dr BrandonOpen to recruitmentNCT02834780
(UHN) OZM-067 / LuNETA Prospective Single-Arm, Multi-Centre, Study of the Efficacy and Safety of Lutetium-177 Octreotate (Lu-DOTATATE) Treatment with individualized dosimetry in Patients with 68Ga-DOTATATE identified Somatostatin Receptor positive Neuroendocrine TumorsJuergens, Dr RosalynOpen to recruitmentNCT02743741
RTOG 1112Randomized Phase III Study of Sorafenib Versus Stereotactic Body Radiation Therapy Followed by Sorafenib in Hepatocellular CarcinomaSwaminath, Dr AnandOpen to recruitmentNCT01730937
(AstraZeneca) D933GC00001 / EMERALD-1A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Transarterial Chemoembolization (TACE) in Combination with either Durvalumab Monotherapy or Durvalumab plus Bevacizumab Therapy in Patients with Locoregional Hepatocellular CarcinomaZbuk, Dr KevinSuspended/On holdNCT03778957
(CCTG) CO.21 / CHALLENGEA Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE)Goffin, Dr JohnSuspended/On holdNCT00819208
(EXELIXIS) XL184-312 / COSMIC-312A Randomized, Controlled Phase 3 Study of Cabozantinib (XL184) in Combination with Atezolizumab versus Sorafenib in Subjects with Advanced Hepatocellular Carcinoma Who Have Not Received Previous Systemic Anticancer TherapyMeyers, Dr BrandonSuspended/On holdNCT03755791
(Merck) MK-3475-966Phase 3 Randomized, Double Blind Study of Pembrolizumab Plus Gemcitabine/Cisplatin versus Placebo Plus Gemcitabine/Cisplatin as First-Line Therapy in Participants with advanced/Unresectable Biliary Tract CarcinomaKazemi, Dr GhazalehSuspended/On holdNCT04003636
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