Head and Neck

Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(CCTG) HN.9/LA-OSCCRandomized Phase II Study of Cisplatin plus Radiotherapy versus Durvalumab plus Radiotherapy followed by Adjuvant Durvalumab versus Durvalumab plus Radiotherapy followed by Adjuvant Tremelimumab and Durvalumab in Intermediate Risk HPV-Positive Locoregionally Advanced Oropharyngeal Squamous Cell Cancer (LA-OSCC)Meyers, Dr BrandonOpen to recruitmentNCT03410615
(GSK) 209229 / INDUCE-3A Randomized, Open-label, Adaptive, Phase II/III Study of Pembrolizumab with or without GSK3359609 for First-Line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaMeyers, Dr BrandonOpen to recruitmentNCT04128696
(LHRI) RADIO/Cisplatin Hearing Loss/Cisplatin HD vs LDRandomized Assessment of Cisplatin Dosing Interval for Ototoxicity in the treatment of locally advanced head and neck squamous cell carcinoma (LAHNSCC) undergoing curative concurrent chemoradiotherapy (RADIO)Meyers, Dr BrandonOpen to recruitmentNCT03649048
(Galera) GTI-4419-301 / ROMANROMAN: Reduction in Oral Mucositis with Avasopasem Manganese (GC4419) – Phase 3 Trial in Patients Receiving Chemoradiotherapy for Locally-Advanced, Non-Metastatic Head and Neck CancerMeyers, Dr BrandonSuspended/On holdNCT03689712
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