Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
IND.227A Phase II Randomized Study of Pembrolizumab in Patients with Advanced Malignant Pleural MesotheliomaGoffin, Dr JohnOpenNCT02784171
SandpiperA Phase 1/2, Multicenter, Open-Label Trial of MG1 Maraba Expressing MAGEA3 (MG1-MAGEA3), with Adenovirus Vaccine Expressing MAGE-A3 (Ad-MAGEA3), in Combination with Pembrolizumab in Patients with Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC)Juergens, Dr RosalynOpenNCT02879760
BR.31A Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 In Completely Resected Non-Small Cell Lung Cancer.Juergens, Dr RosalynOpenNCT02273375
BR.34A Randomized Trial of Durvalumab (MEDI4736) and Tremelimumab +/- Platinum Based Chemotherapy in Patients with Metastatic (Stage IV) Squamous or Non-Squamous Non-Small Cell Lung Cancer (NSCLC)Juergens, Dr RosalynOpenNCT03057106
CA018001A Phase 2, Fast Real-time Assessment of Combination Therapies in Immuno-ONcology Study in
Subjects with Advanced Non-small Cell Lung Cancer (FRACTION-Lung)
Juergens, Dr RosalynOpenNCT02750514
CLDK378A2112A multi-center, randomized open label study to assess the systemic exposure, efficacy, and safety of 450 mg ceritinib taken with a low-fat meal and 600 mg ceritinib taken with a low-fat meal as compared with that of 750 mg ceritinib taken in the fasted state in adult patients with ALK rearranged (ALK-positive) metastatic non-small cell lung cancer (NSCLC)Juergens, Dr RosalynOpenNCT02299505
Debio1143-NSCLC-105A phase-Ib dose-finding study of the SMAC mimetic Debio 1143 when given in combination with the anti-PD-L1 antibody avelumab to patients with advanced solid malignancies and, in an expansion cohort, to patients with advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) after platinum-based therapyJuergens, Dr RosalynOpenNCT03270176
LINNEARRE IPhase I study of neo-adjuvant stereotactic body radiotherapy (SBRT) in operable patients with borderline resectable locally advanced non-small cell lung cancer (NSCLC)Tsakiridis, Dr TheosOpenNCT02433574
M14-361A Phase 1 Escalation and Phase 2 Randomized Double-Blind Study of Veliparib in Combination with Carboplatin Etoposide as a Therapy of Treatment Naïve Extensive Stage Disease Small Cell Lung CancerEllis, Dr PeterOpenNCT02289690
M16-289A Randomized, Open-Label, Multicenter, Phase 3 Study of Rovalpituzumab Tesirine Compared with
Topotecan for Subjects with Advanced or Metastatic DLL3high Small Cell Lung Cancer (SCLC) who have First Disease Progression During or Following Front-Line Platinum-Based Chemotherapy
Ellis, Dr PeterOpenNCT03061812
OCOG-2013-LUSTREA Randomized Trial of Medically-Inoperable Stage I Non-Small Cell Lung Cancer Patients Comparing Stereotactic Body Radiotherapy Versus Conventional Radiotherapy (LUSTRE)Swaminath, Dr AnandOpenNCT01968941
OCOG-2014-ALMERAA Phase II Study to Investigate a Combination of Metformin with Chemo-Radiotherapy in Patients with Locally Advanced Non-Small Cell Lung Cancer Advanced Lung CancerTsakiridis, Dr TheosOpenNCT02115464
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