Lung

Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
Ad/MG1-MAGEA3-001 (Sandpiper)A Phase 1/2, Multicenter, Open-Label Trial of MG1 Maraba Expressing MAGEA3 (MG1-MAGEA3), with Adenovirus Vaccine Expressing MAGE-A3 (Ad-MAGEA3), in Combination with Pembrolizumab in Patients with Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC)Juergens, Dr RosalynOpenNCT02879760
BAY 94-9343/15743 Phase II trial of anetumab ravtansine (BAY 94-9343) in patients with advanced or metastatic malignant pleural mesothelioma (MPM) overexpressing mesothelin after first line treatment with platinum in combination with pemetrexedEllis, Dr PeterOpenNCT02610140
BR.31A Phase III Prospective Double Blind Placebo Controlled Randomized Study of Adjuvant MEDI4736 In Completely Resected Non-Small Cell Lung Cancer.Juergens, Dr RosalynOpenNCT02273375
BRC.6A BIOMARKER-DRIVEN MASTER PROTOCOL FOR PREVIOUSLY TREATED SQUAMOUS CELL LUNG CANCER (LUNG-MAP)Ellis, Dr PeterOpenNCT02154490
CA001030A Phase 1/2 Multicenter Study of BMS-986012 in Subjects with Relapsed/Refractory Small Cell Lung CancerJuergens, Dr RosalynOpenNCT02247349
CLDK378A2112A multi-center, randomized open label study to assess the systemic exposure, efficacy, and safety of 450 mg ceritinib taken with a low-fat meal and 600 mg ceritinib taken with a low-fat meal as compared with that of 750 mg ceritinib taken in the fasted state in adult patients with ALK rearranged (ALK-positive) metastatic non-small cell lung cancer (NSCLC)Juergens, Dr RosalynOpenNCT02299505
IND.227A Phase II Randomized Study of Pembrolizumab in Patients with Advanced Malignant Pleural MesotheliomaGoffin, Dr JohnOpenNCT02784171
LINNEARRE IPhase I study of neo-adjuvant stereotactic body radiotherapy (SBRT) in operable patients with borderline resectable locally advanced non-small cell lung cancer (NSCLC)Tsakiridis, Dr TheosOpenNCT02433574
OCOG-2013-LUSTREA Randomized Trial of Medically-Inoperable Stage I Non-Small Cell Lung Cancer Patients Comparing Stereotactic Body Radiotherapy Versus Conventional Radiotherapy (LUSTRE)Swaminath, Dr AnandOpenNCT01968941
OCOG-2014-ALMERAA Phase II Study to Investigate a Combination of Metformin with Chemo-Radiotherapy in Patients with Locally Advanced Non-Small Cell Lung Cancer Advanced Lung Cancer Tsakiridis, Dr TheosOpenNCT02115464
ASTRISOpen Label, Multinational, Multicenter, Real World Treatment Study of Single Agent AZD9291 for Patients with Advanced/Metastatic Epidermal Growth Factor Receptor (EGFR) T790M Mutation Positive Non Small Cell Lung Cancer (NSCLC) Who Have Received Prior Therapy with an EGFR Tyrosine Kinase Inhibitor (EGFRTKI)The ASTRIS Study Juergens, Dr RosalynOpenNCT02474355
IND.219A RANDOMIZED PHASE II TRIAL OF SELUMETINIB IN PATIENTS RECEIVING STANDARD PEMETREXED AND CISPLATIN CHEMOTHERAPY FOR THE TREATMENT OF ADVANCED OR METASTATIC KRAS WILDTYPE OR UNKNOWN NON-SQUAMOUS NON-SMALL CELL LUNG CANCERGoffin, Dr JohnSuspendedNCT02337530
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