Melanoma

Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(CCTG) IND.224A Phase II Study of Concurrent Dabrafenib and Trametinib with Stereotactic Radiation in the Management of Patients with BRAF Mutation-Positive Malignant Melanoma and Brain MetastasesMcWhirter, Dr ElaineOpen to recruitmentNCT02974803
(CCTG) ME.13/STOP-GAPA Randomized Phase III Study of Duration of Anti-PD-1 Therapy in Metastatic Melanoma (STOP-GAP)McWhirter, Dr ElaineOpen to recruitmentNCT02821013
(Novartis) CDRB436F2410 Open-label, phase III-b study to assess the utility of a new algorithm of improved AE-management for pyrexia syndrome and to explore its impact on the pyrexia syndrome AE driven permanent discontinuation rate in the adjuvant treatment with dabrafenib plus trametinib of high-risk stage III BRAF V600 mutation-positive melanoma after surgical resectionMcWhirter, Dr ElaineOpen to recruitmentNCT03551626
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