Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(UHN) OCTANEOntario-wide Cancer TArgeted Nucleic acid Evaluation (OCTANE)Hotte, Dr Sebastien OpenNCT02906943
(Tesaro) 4010-01-001 / GARNETA Phase 1 Dose Escalation and Cohort Expansion Study of TSR-042, an anti-PD-1 Monoclonal Antibody, in Patients with Advanced Solid TumorsElit, Dr LaurieOpenNCT02715284
(Debio) 1143-NSCLC-105A phase-Ib dose-finding study of the SMAC mimetic Debio 1143 when given in combination with the anti-PD-L1 antibody avelumab to patients with advanced solid malignancies and, in an expansion cohort, to patients with advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) after platinum-based therapyJuergens, Dr RosalynOpenNCT03270176
(AstraZeneca) D4191C00068 / STRONGAn Open-Label, Multi-Centre, Safety Study of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies (STRONG) – Core Protocol; Module A – Post-Chemotherapy Urothelial and NonUrothelial Carcinoma of the Urinary TractHotte, Dr Sebastien OpenNCT03084471
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