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Clinical Trial NameClinical Trial Full TitlePrincipal InvestigatorProject site statusClinical trials gov number
(HHS) CRUSSHStereotactic body radiotherapy (SBRT) boost following urgent 3D conformal radiotherapy in the treatment of metastatic epidural spinal cord compression (SCC): A phase I feasibility trialDonovan, Dr ElysiaOpen to recruitmentNCT03529708
(Tesaro) 4010-01-001 / GARNETA Phase 1 Dose Escalation and Cohort Expansion Study of TSR-042, an anti-PD-1
Monoclonal Antibody, in Patients with Advanced Solid Tumors
Elit, Dr LaurieOpen to recruitmentNCT02715284
(Debio) 1143-NSCLC-105A phase-Ib dose-finding study of the SMAC mimetic Debio 1143 when given in combination with the anti-PD-L1 antibody avelumab to patients with advanced solid malignancies and, in an expansion cohort, to patients with advanced or metastatic Non-Small Cell Lung Cancer (NSCLC) after platinum-based therapyJuergens, Dr RosalynOpen to recruitmentNCT03270176
(UHN) OCTANEOntario-wide Cancer TArgeted Nucleic acid Evaluation (OCTANE)Hotte, Dr SebastienSuspended/On holdNCT02906943
(Roche) NP39487OPEN-LABEL, DOSE FINDING AND EXPANSION PHASE IB STUDY TO EVALUATE THE SAFETY,
PHARMACOKINETICS AND CLINICAL ACTIVITY OF RO6870810 AND ATEZOLIZUMAB (PD-L1 ANTIBODY) IN PATIENTS WITH ADVANCED OVARIAN CANCER OR TRIPLE NEGATIVE BREAST CANCER
Hirte, Dr HalSuspended/On holdNCT03292172
(AstraZeneca) D4191C00068 / STRONGAn Open-Label, Multi-Centre, Safety Study of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies (STRONG) – Core Protocol; Module A – Post-Chemotherapy Urothelial and NonUrothelial Carcinoma of the Urinary TractHotte, Dr SebastienSuspended/On holdNCT03084471
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